Physiology and Biophysics
Seminar Series
Jun
2
Thu
2022
HOLDING – co-host with Bloedel
SHACS series
One receptor, two surprises: unexpected mGluR-mediated neuromodulation in sound localization circuits
Yong Lu, PhD
Professor of Anatomy and Neurobiology
College of Medicine
Northeast Ohio Medical University (NEOMED)
Abstract: Neuromodulation affects brain function and development. We investigated neuromodulation mediated by group I metabotropic glutamate receptors (mGluR I) in the brainstem sound localization circuits. Activation of mGluR I exerts differential modulation of synaptic transmission depending on the transmitter type and its release mode. Furthermore, the modulation generates temporally patterned spontaneous synaptic responses, implying a potential central mechanism underlying the spontaneous activity necessary for the development of the sound localization circuits. website: https://www.neomed.edu/directory-profile/lu-yong-138787/Jun
23
Thu
2022
Identifying mechanisms of cognitive computations from spikes
Tatiana Engel, Ph.D.
Assistant ProfessorCold Spring Harbor Laboratory
website: https://www.cshl.edu/research/faculty-staff/tatiana-engel/
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