Sharona Gordon and Bill Zagotta are co-chairs of the Program for the 2012 Biophysical Society Meeting in San Diego. With more than 3,700 abstracts submitted, the meeting is expected to attract about 9,000 registered attendees from all over the world. Sharona and Bill worked with their Program committee to plan 21 symposia, 3 mini-symposia, and 5 workshops. New topics this year include “Soft Lithography for Biology” and “Biofuels.” Planning the event has been underway for over a year. Putting on the Annual Meeting is the major function of the Society.