Associate Professor and Vice Chair, Department of Physiology and Membrane Biology, University of California, Davis.
Abstract: Kv2 proteins form voltage-gated potassium ion channels that contribute to a wide variety of physiological responses throughout our bodies. In neurons, Kv2 proteins are abundant on and near the cell soma, where their unique voltage-gating regulates repetitive firing of action potentials. This seminar investigates mechanisms of modulators that shed light on the peculiar relation between voltage sensing and pore opening of Kv2 channels.
website: https://basicscience.ucdmc.ucdavis.edu/Sack_and_Yarov-Yarovoy_Labs/
Host: Oscar Vivas